- Journal of the Turkish Chemical Society Section A: Chemistry
- Vol: 3 Issue: 1
- Synthesis of substituted quinolinone ketones derived with some five, six and seven-membered heterocy...
Synthesis of substituted quinolinone ketones derived with some five, six and seven-membered heterocycles
Authors : Magdi Ahmed, Hany Hassanin, Mohamed Abass, Shimaa Badran
Pages : 27-45
Doi:10.18596/jotcsa.91001
View : 10 | Download : 7
Publication Date : 2016-01-11
Article Type : Other
Abstract :Abstract: The synthesis of a series of new quinolinyl ketones substituted with some five, six and seven-membered diaza-heterocycles is described. Efficient base or acid-catalyzed nucleophilic heterocyclization of 6-ethyl-4,5-dioxo-5,6-dihydro-4 H -pyrano[3,2- c ]quinoline-3-carboxaldehyde with a variety of nitrogen and/or carbon 1,2-, 1,3-, and 1,4-binucleophiles afforded the target ketones in good yields. The structure of all new products was established on basis of their spectral and analytical data.Keywords :