The Effect of Granulocyte Colony Stimulating Factor Use in addition to Classical Treatment on Prognosis and Blood Values in Patients with Feline Panleukopenia

Authors : Botan Kizilkaya, Erdal Kara

Pages : 357-364

View : 172 | Download : 459

Publication Date : 2023-09-30

Article Type : Research

Abstract :Feline panleukopenia virus is a notable disease in cats and has a very contagious progression especially in young and not vaccinated individuals. Worse still, conventional treatments have a below 50 % success rate in treating this disease. This study investigated the prognostic success of administering a granulocyte colony-stimulating factor, filgrastim, with the conventional treatment for cats with feline infectious enteritis. The study had 48 sick individuals, 31 of whom had conventional + filgrastim treatment, whereas 17 had only conventional treatment (control group). A ratio of 93.61 % of all individuals showed leukopenia and 82.97 % of all individuals had neutropenia. The ratio of not vaccinated individuals in the study sample was 92.3 %. The recovery ratio in the study group in which filgrastim was administered was 72.41 %, whereas this ratio was 58.82 % in the control group, yet the difference was not statistically significant (p˃0.9999). In the blood count values of the control group, there was no statistically significant difference between pre-treatment and post-treatment measurements. On the other hand, WBC, LYM, and NEU values were significantly different in the study group with additional filgrastim treatment (p<0.001). The study results indicated that vaccination is critical in protection against feline parvovirus, diarrhea, and vomiting symptoms in the first diagnosis are noteworthy, and using filgrastim in addition to the conventional treatment did not have a considerable impact on prognosis, although it did ameliorate blood values.
Keywords : Feline panlökopeni virus, Filgrastim, Lökopeni, Koloni sitümile edici faktör, Tedavi