Serum Levels of Mid-Regional Pro-adrenomedullin and Soluble Triggering Receptor Expressed on Myeloid Cells in Cattle with Pneumonia

Authors : Mert Sezer, Enes Akyüz, Oğuz Merhan, Uğur Aydin, Umut Bati, Uğur Yildiz, Tahir Gezer, Ekin Emre Erkiliç, Ali Haydar Kirmizigül, Gürbüz Gökçe

Pages : 109-117

Doi:10.30607/kvj.1215383

View : 15 | Download : 5

Publication Date : 2023-03-31

Article Type : Research

Abstract :This study aimed to determine the serum levels of two inflammatory biomarkers, named, mid-regional pro-adrenomedullin (MR-Pro ADM) and soluble triggering receptor expressed on myeloid cells (sTREM-1), in cattle diagnosed with pneumonia. For this purpose, 40 patient female cattle, which were aged 2-7 years and displayed coughing, dyspnea, nasal discharge, anorexia and abdominal respiration, and 15 healthy female cattle within the same age range, were evaluated. The diseased cattle underwent clinical and radiological examinations and were sampled for blood prior to receiving treatment. The healthy subjects also underwent clinical examination and were sampled for blood once. Blood samples were used for biochemical and hematological measurements. While the diseased group had higher serum levels of MR-Pro ADM (86.38±6.33), compared to the healthy control group (61.81±4.96); the pneumonic cattle had lower levels of sTREM-1 (75.93±1.86), in comparison to the healthy group (96.55±9.13). In conclusion: MR-Pro ADM and sTREM-1 levels are very important diagnostically in cattle with pneumonia
Keywords : Mr-Pro-Adm, Pnömoni, Sığır, sTREM-1