The Effect of Clinical, Laboratory Findings and Parenchymal Infiltration Features on the Diameter of the Main Pulmonary Artery in COVID-19 Pneumonia

Authors : Deniz Esin Tekcan Şanli

Pages : 274-279

Doi:10.31067/acusaglik.931060

View : 35 | Download : 13

Publication Date : 2022-03-15

Article Type : Research

Abstract :Purpose: The main pulmonary artery diameter is an indirect indicator of pulmonary vascular bed resistance. In this study, it was aimed to reveal which parameters are associated with respiratory distress by evaluating the parameters affecting the diameter of the main pulmonary artery in cases with COVID-19 pneumonia. Methods: The relationship between comorbid diseases, clinical findings, laboratory values, pulmonary infiltration features, and main pulmonary artery diameter (MPAD) was statistically evaluated. Results: When MPAD 27.5 mm was considered as enlargement; it was significantly wider in smokers in COVID-19 pneumonia (p<0.05). It was statistically shown that there was not association with diabetes, hypertension, asthma, or COPD and MPAD (p>0.05). It was observed that MPAD was associated with shortness of breath (p=0.039; p<0.05) but not with cough and fever (p>0.05). Also, it was found that MPAD was significantly wider in cases with high CRP and LDH values (p=0.008; p<0.01, p=0.011; p<0.05, respectively). While MPAD did not differ significantly in those with ground-glass infiltration; MPAD was significantly larger in those with infiltration in the form of crazy-paving or consolidation (p<0.05). While there is no significant variation in MPAD in those with periferobasal involvement; MPAD was significantly wider in cases with central or mixed infiltration (p<0.05). Conclusion: It is possible to indirectly predict respiratory distress in COVID-19 patients by measuring MPAD, which is associated with respiratory distress. Smoking, CRP and LDH values, central infiltration in the pattern of crazy-paving or consolidation are related with increased MPAD in COVID-19 pneumonia.
Keywords : COVID-19, SARS-CoV-2, respiratory distress, main pulmonary artery diameter, chest CT, crazy-paving, ground-glass opacity