Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Authors : Şemsinnur Göçer, Özlem Balbaloğlu

Pages : 119-125

Doi:10.31067/acusaglik.948574

View : 38 | Download : 13

Publication Date : 2022-01-01

Article Type : Research

Abstract :Objective: Given that there is limited number of studies investigated joint effect of vitamin D and parathyroid hormone (PTH) in frailty syndrome, we aimed to evaluate association of frailty with serum vitamin D and PTH levels. Materials and Methods: This is a cross-sectional study conducted on individuals aged >65 years. In this cross-sectional study, data were collected using sociodemographic data sheet, Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight (FRAIL) scale and Study of Osteoporotic Fracture (SOF) index via face-to-face interview. The study included data from 513 subjects. Chi-square test was used in analyses. A p value<0.05 was considered as statistically significant. Results: The mean age was 71.9±6.4 years in the study population. Of the subjects, 75.2% were women and 77.2% were married while 61.8% were illiterate and 99.2% had own income. The prevalence of frailty elder was found as 46.8% by FRAIL scale and 51.3% by SOF index while pre-fail elder prevalence was found as 45.2% by FRAIL scale and 33.3% by SOF index. Conclusion: It was found that frail elder prevalence was increased by advancing age, female gender and presence of comorbidity and that low serum vitamin D and elevated PTH levels were closely associated with prevalence of frail elder.
Keywords : Fraility, Vitamin D, Parathyroid, Elderly