Toplumdan Kazanılmış Metisiline Dirençli S. aureus

Authors : Hayati Güneş, Emel Sesli Çetin

Pages : 83-90

View : 32 | Download : 15

Publication Date : 2012-06-01

Article Type : Other

Abstract :CA-MRSA community-acquired, or community-associated Staphylococcus aureus has appeared with increasing frequency and is now epidemic within certain community populations. Whereas hospital associated MRSA is almost always found in persons with established risk factors associated with prior medical treatment, these are not present in CA-MRSA. This form causes serious skin and soft tissue infections in otherwise healthy persons who have not been recently hospitalized or undergone invasive medical procedures. CA-MRSA has been identified most frequently among prisoners, athletes, children, men who have sex with men, and military recruits. A major difference between the two types that CA-MRSA possesses a potent toxin called PantonValentine leukocidin, which attacks infection-fighting leukocytes. The most serious form of CA-MRSA infection causes necrotizing fasciitis. Also it causes serious necrotizing pneumonia and increased complications of hematogenous osteomiyelitis. Two clones strains of staph, called USA300 and USA400, are associated with the CA-MRSA. CA-MRSA has stphylococcal casette chrosome SCC mec IV and V as resistance genes unlike HA-MRSA which has I, II and III SCC mec. CA-MRSA is still susceptible to several antibiotic classes outside of the beta-lactam group and macrolides. Bacteria can develope resistance to other antibiotics. Therefore clinicians must be careful at use of them
Keywords : methicillin resistance, Staphylococcus aureus