Stabil Kronik Obstrüktif Akciğer Hastalığında İnflamatuar Belirteçler ve Hastalık Ağırlığı ile Karotis Arter İntima-Media Kalınlığının İlişkisi

Authors : Engin Aynaci, Birsen Pınar Yildiz, Aysun Aynaci, Gönenç Ortaköylü, Fırat Çetinkaya, Emel Çağlar

Pages : 146-151

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Publication Date : 2011-09-01

Article Type : Research

Abstract :Aim: The aim of the study was to evaluate the relationship between intimamedia thickness of carotid artery and inflammatory markers and severity of disease in patients with COPD. Materials and method: Fifty-three stable COPD patients 38males/15females with median age 56,9±54 years old were included. Right and left carotid arteries were examined with a duplex scanner. Intima-media thickness IMT measurements of the carotid artery are compared to levels of CRP, fibrinojen, leucocyte counts, BMI, and stage of the disease. Results: There is significant relationship between the stage of COPD and the levels of CRP elevation p=0.01 . But no relationship was found between intima media thickness and the parameters we have investigated, including CRP. Conclusion: There have to be made new extended studies, to examine the effects of COPD, as a systemic inflamatory disease, on vasculer system
Keywords : Inflammation, Chronic obstructive lung disease, intima media thickness, Carotid artery