A case of adult-onset Still’s disease that does not fulfill Yamaguchi’s and Fautrel’s criteria: Sensitivity limitations and improvement proposal

Authors : Alper Tuna Güven, Buğra Hatipoğlu, Beyazıt Kayaoğlu, Nermin Şerifli, Aslı Özçiçek, Tuba Işıl Geleri

Pages : 102-107

Doi:10.46310/tjim.1410876

View : 72 | Download : 77

Publication Date : 2024-04-29

Article Type : Other

Abstract :Adult-Onset Still\'s Disease (AOSD) is an uncommon inflammatory condition that lacks a universally accepted diagnostic test. The clinical presentation comprises symptoms such as fever, rash, joint pain, sore throat, swelling of lymph nodes, and enlargement of the liver and spleen. The diagnostic criteria developed by Yamaguchi and Fautrel are commonly employed because of their great sensitivity and specificity. However, there are cases in which individuals may not meet these criteria but still demonstrate symptoms of AOSD. In this case, we report an elderly patient who has been diagnosed with AOSD but does not meet the criteria for any of these criteria. We discussed the factors contributing to impaired sensitivity and put forth various suggestions to enhance the sensitivity of these criteria.
Keywords : Fever, Sensitivity and Specificity, Adult-Onset Still