Focal Segmental Glomerulosclerosis with Sjogren Syndrome: A Case Report

Authors : Mehmet Sezen, Abdülmecit Yildiz, Kamil Dilek, Mustafa Güllülü, Mahmut Yavuz, Ayşegül Oruç, Mehmet Fethullah Aydin, Alparslan Ersoy

Pages : 107-109

Doi:10.46310/tjim.876204

View : 28 | Download : 7

Publication Date : 2021-03-07

Article Type : Other

Abstract :Sjogren's syndrome (SjS) is a chronic, slow-progressing, autoimmune and lymphoproliferative disease. The main symptoms of the syndrome are xerostomia and keratoconjuctivitis sicca as a result of chronic inflammatory infiltration of the salivary and lacrimal glands. Focal Segmental Glomerulosclerosis complicating primary Sjögren's syndrome is extremely rare. We report on a 39-year-old woman with 5 years history of sjogren syndrome who was found to have nephrotic syndrome. Histopathological findings in kidney biopsy compatible with focal segmental glomerulosclerosis. Steroid therapy was initiated (oral prednisolone at a dose of 15 mg/day) and Cyclosporine 2 * 100mg/d. FSGS, which is associated with sjögren's syndrome, was considered suitable for the presentation because of its rare occurrence
Keywords : sjogren syndrome, focal segmental glomerulosclerosis, nephrotic syndrome