Synthesis of new oxindole derivatives containing benzothiazole and thiazolidinone moieties using nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as catalyst

Authors : Robabeh Baharfar, Narges Shariati

Pages : 235-0

Doi:10.3906/kim-1408-26

View : 19 | Download : 11

Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :A facile one-pot synthesis of novel oxindole derivatives bearing benzothiazolylmethyl-2-thioxothiazolidin-4-one was accomplished via one-pot reaction of 5-oxoindolinylidene rhodanine-3-acetic acid derivatives, 2-aminothiophenol, and triphenyl phosphite in the presence of tetrabutylammonium bromide (TBAB) and nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as heterogeneous reusable nanocatalyst. The target compounds were obtained in excellent yields (85%--92%) and short reaction times under fairly mild reaction conditions.
Keywords : Oxindole derivatives, benzothiazoles, 4-thiazolidinones, nano silica-bonded 5-n-propyl-octahydro-pyrimido [1, 2-a]azepinium chloride, nano silica-supported catalyst