Transition Metal Compound Mediated Reduction of a-Amino Acids to 1,2-Amino Alcohols with NaBH4 in Water

Authors : Ayhan S. Demir, Idris M. Akhmedov, Özge Şeşenoğlu

Pages : 123-126

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Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.
Keywords : Turk. J. Chem., 23, (1999), 123-126. Full text: pdf Other articles published in the same issue: Turk. J. Chem., vol.23, iss.2.