Reactions of N-Aminopyrimidine Derivatives with 1,3-Dicarbonyl Compounds

Authors : Zülbiye Önal, Behzat Altural

Pages : 401-406

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Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :The reactions of 1-Amino-pyrimidine derivatives (1) and some 1,3-dicarbonyl compounds (2) were realized in the presence of p-toluensulfonic acid catalyst to give convenient enamine (3) and/or imine derivatives (4). In the same way, the enamine (5) and/or imine derivatives (6) were synthesized using (1) and 1,3-indanedione which is one of the different 1,3-dicarbonyl compounds. The molecular structures of all the prepared compounds were determined by 1H-nmr, 13C-nmr, i.r. spectra and elemental analyses, and were drawn by taking imine-enamine tautomerism into account.
Keywords : Enamine, Imine, 1, 3-Diketone, Addition reaction