Synthesis and Antimicrobial Testing of Some Flavonylsulfonamide Derivatives

Authors : Gülgün Ayhan Kilcigil, Oya Bozdağ Dündar, Rahmiye Ertan

Pages : 461-466

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Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :Six new 4-amino-N-heteroaryl,N-[(2-phenyl-4H-1-benzopyran-4- oxo-6-yl)metil]benzensulfonamide derivatives, (3a-3f) were prepared by reacting 6-bromomethylflavone with the corresponding sulfonamide derivatives and their antimicrobial activities against Escherichia coli were evaluated. All of the compounds exhibited better activity (except compound 3c) than the corresponding sulfonamide derivatives.
Keywords : Flavonylsulfonamides, synthesis, antimicrobial