A Convenient Method for the Preparation of 2-Aminobenzophenone Derivatives under Ultrasonic Irradiation

Authors : Javad Safaei-ghomi, Manouchehr Fadaeian, Alireza Hatami

Pages : 89-95

View : 23 | Download : 11

Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :A quick and convenient method for the preparation of 2-aminobenzophenone derivatives is described. This approach consists of the nucleophilic substitution reaction of nitrobenzenes by phenylacetonitrile under conventional and ultrasonic conditions followed by reduction of the produced 2,1-benzisoxazole to 2-aminobenzophenone. This 2-step reaction was studied by changing the reaction parameters (reaction temperature, ultrasound power, and reaction time). The results clearly demonstrated that using ultrasound irradiation results in a high yield within a short reaction time.
Keywords : Turk. J. Chem., 31, (2007), 89-95. Full text: pdf Other articles published in the same issue: Turk. J. Chem., vol.31, iss.1.