Synthesis and Antifungal Activity of Some Novel N-(4-Phenyl-3-aroylthiazol-2(3H)-ylidene) Substituted Benzamides

Authors : Aamer Saeed, Sabah Zaman, Maryam Jamil, Bushra Mirza

Pages : 585-592

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Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.
Keywords : N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene) substituted benzamides, antifungal