Highly stereoselective and efficient synthesis of the dopa analogue in pepticinnamin E via enantioselective hydrogenation of dehydroamino acids

Authors : Highly Stereoselective And Efficient Syn In

Pages : 181-186

View : 11 | Download : 7

Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :An efficient and new method was developed to prepare the dopa analogue 11 in natural pepticinnamin via catalytic hydrogenation of dehydroamino acids (DDAA) with a good yield and ee. Product 11 is a key intermediate towards the total synthesis of pepticinnamin E and its analogues.
Keywords : Synthesis, dopa analogue, enantioselective hydrogenation, dehydroamino acid.