Sulfonic acid-functionalized silica: a remarkably efficient heterogeneous reusable catalyst for the one-pot synthesis of 1,4-dihydropyridines

Authors : Behzad Mohammadi, Sayyed Mohammad Hosseini Jamkarani, Taghi A. Kamali

Pages : 613-619

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Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :An efficient one-pot method for the synthesis of 1,4-dihydropyridines from b-dicarbonyl compounds, aldehyde, and ammonium acetate is reported using sulfonic acid-functionalized silica at 90 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable (up to 300 °C), reusable, and efficiently used under reaction conditions.
Keywords : 1, 4-Dihydropyridine, b-dicarbonyl compounds, solid acid, SiO2-R-SO3H, heterogeneous catalyst