Enantioselective Henry reaction catalyzed by a novel L-(+)-aspartic acid-derived Schiff base ligand and Cu(II) ion

Authors : Gamze Koz, Demet Astley, Stephen Thomas Astley

Pages : 553-560

Doi:10.3906/vet-1110-20

View : 15 | Download : 6

Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :Mild and efficient enantioselective Henry reactions of nitromethane with various aldehydes were catalyzed by a novel L-(+)-aspartic acid-derived Schiff base ligand in the presence of Cu(II) ions, affording the corresponding adducts in high yields (up to 96%) and enantioselectivities (up to 92% ee).
Keywords : Enantioselective Henry reaction, chiral Schiff base, L-(+)-aspartic acid