Synthesis of a-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect

Authors : Çiğdem Yildirim, Çiğdem Yolaçan, Feray Aydoğan

Pages : 101-109

Doi:10.3906/vet-1107-26

View : 17 | Download : 9

Publication Date : 9999-12-31

Article Type : Makaleler

Abstract :The synthesis of a-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-a-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.
Keywords : a-Aminonitrile, Strecker synthesis, montmorillonite K10, dicationic phosphonium salt