The effect of vitamin D levels on prognosis of patients with facial paralysis

Authors : Ayşe Enise Göker, Semih Karaketir, Maide Hacer Alagöz, Ayca Başkadem Yilmazer, Hüseyin Sari, Hasan Sami Bircan, Nilgün Başaran

Pages : 118-122

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Publication Date : 2020-12-15

Article Type : Research

Abstract :Objectives: This study aims to investigate the serum 25-hydroxyvitamin D3 [25 OH D3] levels of patients with Bell’s palsy BP , and to evaluate their role in prognosis and their impact on the disease etiology. Patients and Methods: A total of 49 patients 30 males, 19 females; mean age: 42.2±13.6 years; range, 19 to 67 years who were diagnosed with BP and treated at our clinic between October 2019 and April 2020 were included. Blood samples were collected within 24 h after the onset of BP symptoms, and a standard oral pharmacological treatment was administered with prednisolone 1 mg/kg for 10 days and acyclovir 700 mg/day for six days. All patients were graded according to the House-Brackmann scale HBS . The patients were divided into three groups as Grade 2, Grade 3, Grade ≥4. The patients with BP were further divided into two groups as healed n=36 and not-healed ones n=13 . The vitamin D levels of the groups were compared. Results: Eleven 22% patients were in the Grade 2 group, 21 43% patients were in the Grade 3 group, and 17 35% patients were in the Grade ≥4 group. A significant decrease in vitamin D levels was observed in the patients with HBS Grade ≥4, compared to Grade 3 and Grade 2 groups p=0.002 and p<0.001, respectively . Vitamin D levels were significantly higher among the patients without sequelae than those with sequelae p<0.001 . Conclusion: Our study results indicate that vitamin D deficiency can affect prognosis of BP patients.
Keywords : Bell’s palsy, facial paralysis, vitamin D deficiency