The impact and relationship of inflammatory markers and radiologic involvement in the COVID-19 patients

Authors : Merve Sefa Sayar, Dilek Bulut, Sebahattin Çelik, Veysel Burulday, Remzi Sarikaya, Nurettin Kurt

Pages : 416-421

Doi:10.32322/jhsm.904196

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Publication Date : 2021-07-15

Article Type : Research

Abstract :Aim: In the study, it was aimed to investigate the relationship between inflammatory markers and radiology in COVID-19 patients. Material and Method: The study was conducted in the quarantine wards of a tertiary hospital between March and June 2020. Patients with a definite diagnosis of COVID-19 were included in the study. The lung damage of the patients caused by COVID-19 was determined by computed tomography and the relationship between lung damage and inflammatory markers was examined. Results: The mean age of 259 COVID-19 patients included in the study was 61.96 ± 14.076. Except for thrombocytopenia, all variables such as ferritin, D-dimer, thoracic computerized tomography (CT) involvement rates were significantly poorer in the patients requiring the care in ICU than the patients in wards (p<0.001). No chronic disease was found in 193 (74.5%) of 259 patients. In multi-variate analyzes, elderly and high thoracic CT involvement rate were determined as independent variables determining the serious disease risks and are important parameters in assessing the need for ICU (p<0.05). Ferritin value, D-Dimer value on the third day of admission, Neutrophil lymphocyte ratio and leukocyte count were found to be correlated with thoracic CT involvement rate (p <0.05). Conclusion: It was observed that there were serious changes in the infection parameters of COVID-19 cases with advanced radiological involvement in the lung.
Keywords : COVID-19, intensive care unit, prognosis, SARS-CoV-2