Binocular Diplopia After A Snakebite

Authors : Fatih Çalişkan, Celal Kati, Hızır Ufuk Akdemir, Yıldıray Çelenk

Pages : 79-81

Doi:10.33706/jemcr.882234

View : 30 | Download : 18

Publication Date : 2021-08-18

Article Type : Other

Abstract :A snakebite is an injury caused by a bite from a snake, often resulting in puncture wounds inflicted by animal’s fangs and sometimes resulting in envenomation. Venom may cause a complex condition that can be local damage, neuromuscular dysfunction, or systemic vascular damage leading to hemolysis. The main cause of mortality and morbidity in snake bites is neurotoxicity, and the main cause of neurotoxicity is sudden neuromuscular paralysis. Synthesis, packaging, transport, and release of the neurotransmitter acetylcholine in the presynaptic field, blockade of postsynaptic nicotinic acetylcholine receptors, acetylcholine esterase inhibition, muscarinic effects of some snake toxins, and inhibition of voltage-gated calcium gates, changes in the neuromuscular junction after snakebite can explain neuromuscular paralysis secondary to the snake bite. We present a case, with bilateral diplopia and ptosis after snakebite, that was recovered after the use of anticholinesterase therapy and antivenom.
Keywords : diplopia, snake bites, antivenins, cholinesterase inhibitors