Is the occurrence of Gestational Diabetes Mellitus in pregnancies higher following In Vitro Fertilization treatment? Why? A retrospective cohort study

Authors : Nuran Nur Aypar Akbağ, Merlinda Aluş Tokat, Sevcan Özöztürk, Elif Ünsal Avdal, Recep Emre Okyay, Ömer Erbil Doğan

Pages : 750-758

Doi:10.30621/jbachs.1543485

View : 39 | Download : 49

Publication Date : 2024-09-30

Article Type : Research

Abstract :Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in pregnancies after IVF treatment and to evaluate the factors that reduce this risk. Material and Methods: This retrospective cohort study was conducted using the medical records of pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019. The data were obtained from medical records and phone interviews. Univariate and multivariate logistic regression analyses were performed. Results: The incidence of GDM was found to be 16.7%. The regression model indicated that the risk of GDM was 4.57 times higher in the age group 36–40 at conception during the IVF cycle than the age group 31–35 (95% CI = 1.18–17.73, p = .028). Furthermore, women who conceived after the second IVF trial had a risk of GDM 3.464 times higher than those that conceived after their first IVF trial (95% CI = 1.07–11.23, p= .038). Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.
Keywords : Gestational Diabetes Mellitus, In Vitro Fertilization, Risk Factors