Erkek İnfertilitesinin Sitogenetiği

Authors : Lütfiye Özpak, Ayfer Pazarbaşi

Pages : 230-245

View : 19 | Download : 8

Publication Date : 2011-12-01

Article Type : Review

Abstract :Infertility by definition, is not to get pregnant within one year of regular sexual relationship without protection, affects 15-20% of reproductive age couples. Approximately 30% of infertility cases are male originated. Male infertility is caused by endocrine-related genetic defects affecting urogenital system function. These defects adversely affect subsequent spermatogenesis, sexual function, fertility, early embryonic stage of sexual maturation. Autosomal and gonosomal, numerical and structural chromosome abnormalities and related syndromes rank at the top causes of male infertility. Similar chromosome abnormalities are detected in male infertility and as the rate of these abnormalities increase, it was found to reduce sperm count especially in azospermic and oligozoospermic men.
Keywords : İnfertilite, Erkek infertilitesi, Hormonal düzenleme Spermatogenez, Seksüel olgunlaşma, Sayısal ve yapısal kromozom anormallikleri