ONE-POT SYNTHESIS OF 2-AMINO-4H-PYRANS AND 2-AMINO-TETRAHYDRO-4H-CHROMENES USING L-PROLINE

Authors : Farahnaz Behbahani

Pages : 387-393

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Publication Date : 2015-10-05

Article Type : Other

Abstract :A one-pot procedure for the synthesis of 2-amino-4-aryl-4 H -pyrans and 2-amino-tetrahydro-4 H -chromenes via the multi-component reaction between aryl aldehydes, β-dicarbonyl compounds and malononitrile in the presence of L -proline-in ethanol under reflux conditions has been developed rapidly and smoothly in good to excellent yields.
Keywords : multicomponent, L-proline, 2-amino-4H-pyrans, chromenes, synthesis