Chemical Composition and Antibacterial Activities of Ethanol Extract of Geodorum attenuatum Griff. (Orchidaceae)

Authors : Hong Thien Van, Thi Ngan Ha Bui, Yen Hoa Mai, Minh Nhat Hao Nguyen, Tan Viet Pham, Van Son Le, Van Dat Doan, Le Pham Tan Quoc

Pages : 613-620

Doi:10.35378/gujs.669681

View : 16 | Download : 11

Publication Date : 2020-09-01

Article Type : Research

Abstract :Geodorum attenuatum has been found in Thailand, China, India and Vietnam, however, the phytochemical composition and antimicrobial activity of G. attenuatum have not been studied yet. In this study, the phytochemical composition of ethanol extract of G. attenuatum tuber was determined using liquid chromatography-mass spectrometry (LC-MS) and evaluated its antibacterial activity of ethanol extract via disk diffusion test. 9 compounds in ethanol extract of G. attenuatum tuber were identified, such as disaccharide, oxoheneicosanoic acid, shikimic acid, chlorogenic acid, 1-Oleoyl-2-acetyl-glycerol, azafrin, 5,6,7-trihydroxyfavone, 2,3-isopropylidene-1-oleoyl-glycerol and trans-docosanoyl ferulate. Moreover, it’s been proved that the ethanol extract of G. attenuatum tuber could inhibit the growth of B. cereus, E. coli, P. aeruginosa, S. enteritidis, S. typhimurium, and S. aureus.
Keywords : Antibacterial activity, G. attenuatum, chemical composition, Ethanol extract, LC-MS