Fetüslerin Sifilizden Zarar Görmemesi: Antenatal Bakım, Maternal ve Neonatal Sonuçlar

Authors : Deniz Şimşek

Pages : 265-271

Doi:10.31832/smj.801833

View : 30 | Download : 10

Publication Date : 2021-06-29

Article Type : Research

Abstract :Objective: Syphilis is a disease as old as human history.Untreated syphilis during pregnancy can cause serious prenatal adverse outcomes, including stillbirth, and congenital syphilis. World Health Organization, obstetrics and gynecology societies recommends screening syphilis at the first antenatal care visit. In this present study, it was aimed to discuss antenatal follow-up, maternal and neonatal outcomes of patients having syphilis infection during pregnancy. Material and Method: Patients diagnosed with syphilis during pregnancy were included in the study. Patients were screened by a Non-Treponomal test and positive results were confirmed by the Treponemal test. Patients data including antenatal examinations, maternal and neonatal results, syphilis treatment, newborn examination findings, syphilis treatment follow-up were obtained and evaluated retrospectively through the hospital registry system and telephone interviews. Results: The total number of patients who were screened with RPR in the first antenatal visit of the pregnancy over two and a half years period was 24427. Ten patients were diagnosed with syphilis by Treponemal test (TP-PA) confirmation. All patients were treated by three doses of Penicillin Benzathine G 2.4 million units via intramuscular route each at a one-week interval. All women gave birth at term without complication. Forty percent of patients diagnosed gestational diabetes mellitus. No congenital syphilis occurred. None of the patients had concomitant HIV and HCV infection. Conclusion: Eradication is possible for syphilis. Early detection at the first antenatal visit and adequate treatment with penicillin would prevent maternal and congenital syphilis, and recover babies from adverse outcomes of syphilis.
Keywords : Non-treponemal test, Treponemal test, Syphilis, syphilis in pregnancy, Penicillin benzathine G