Seroprevalence of patients presenting with a pre-diagnosis of Toxoplasma gondii, Türkiye

Authors : Burcu Aslaner, Serpil Nalbantoğlu, Banuçiçek Yücesan

Pages : 53-60

Doi:10.31362/patd.1314049

View : 53 | Download : 85

Publication Date : 2024-01-01

Article Type : Research

Abstract :Purpose: Toxoplasma gondii is a unicellular protozoan parasite. With this study, the aim was to evaluate the T. gondii test results that came to the General Directorate of Public Health, National Parasitology Reference Laboratory between January 2019 and December 2020. Materials and methods: The seroprevalence were studied with the Sabin-Feldman Dye Test which is gold standard, Anti-T. gondii IgG and IgM and T. gondii IgG avidity with ELISA were evaluated in 1160 patient. The distribution of cases according to gender and age groups was also evaluated statistically. Results: In this study, SFDT was performed on 589 patients from 1160 patients with suspected Toxoplasmosis samples and Anti-T. gondii IgG and IgM tests were studied by ELISA in 478 patients. IgG avidity test by ELISA was performed on 93 cases with positive Anti-T. gondii IgG. In addition to these, cases in which Anti-T. gondii IgM and IgG were studied together and were positive were also evaluated. The number of samples both positive together was 17 (3.6%). According to Anti-T. gondii IgG/IgM results, no significant relationship was found between toxoplasmosis and gender. Moreover, of 93 cases with positive Anti-T. gondii IgG values, 71% had high avidity, 16% had cutoff value and 13% had low avidity. Conclusion: Further studies and surveillance studies should be performed to determine the epidemiology and current prevalence of toxoplasmosis.
Keywords : Avidite, ELISA, Sabin-Feldman Boya Testi, Toxoplasma gondii