Abstract :Climate change impacts are inevitably threatening the future of our planet. Considering the high priority and the urgency of the topic, efforts to mitigate global climate change cannot be limited to government legislations or regulatory actions. Public support and collaboration of citizens are also necessary on the way to low carbon lifestyles. Message framing as a means of persuasive communication is an important tool to accelerate the level of awareness, engagement, support and behavioral change in terms of climate change mitigation efforts. Hence, this paper through a systematic review and content analysis aims to extract and categorize the variables tested in terms of message framing within the context of climate change and to determine the message frames that are found to be the most effective in terms of climate change mitigation efforts. Findings reveal that in terms of dependent and independent variables, the studies can be aggregated but when the most effective message frames are analyzed a general framework could not be observed. Through taking into account the possible reasons, these findings are interpreted at the conclusion of the study. Keywords : Climate change, mitigation, message framing, systematic review, content analysis