- Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi
- Vol: 20 Issue: 2
- The Role of Systemic Inflammatory Response Markers in Differential Diagnosis of Ovarian Tumors
The Role of Systemic Inflammatory Response Markers in Differential Diagnosis of Ovarian Tumors
Authors : Sevgi SERDAR, Günsu KİMYON CÖMERT, Özgün CEYLAN, İrem KAR, Hakan Raşit YALÇIN, Taner TURAN
Pages : 1769-1772
Doi:10.38136/jgon.1278471
View : 17 | Download : 84
Publication Date : 2023-07-03
Article Type : Research Article
Abstract :Aim: The aim of this study is evaluating the predictive value of preoperative inflammatory blood parameters for differential of serous cystadenoma, serous borderline ovarian tumor (BOT) and high-grade serous ovarian (HGSOC) carcinoma. Materials and Method: In this single-center study, we retrospectively enrolled 370 patients with ovarian tumors were divided into three groups. The groups were classified as serous cystadenoma, serous BOT and HGSOC. The potential association of preoperative hemoglobin (Hb), red cell distribution width (RDW), Hb/RDW ratio, ratio of neutrophils to lymphocytes (N/L) and ratio of platelets to lymphocytes (P/L) were analyzed. Results: P/L and N/L were significantly lower in benign serous cystadenoma or serous BOT than HGSOC (p<0.001 and p<0.001). Benign serous cystadenoma was significantly associated with lower median RDW compared to serous BOT and HGSOC (p<0.001). Hb/RDW ratio was significantly lowest in patients with HGSOC and significantly highest in patients with benign serous cystadenoma (p<0.001). Conclusion: Preoperative Hb/RDW can be used as predictor for discrimination of benign serous cystadenoma, serous BOT and HGSOC. N/L and P/L may be considered to distinguish the benign serous cystadenoma and serous BOT from HGSOC.Keywords : Over kanseri, inflamatuar kan belirteçleri, kırmızı hücre dağılım genişliği(RDW)