- Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi
- Vol: 20 Issue: 1
- Evaluation of fetal thymus size in pregnancies complicated with fetal growth restriction
Evaluation of fetal thymus size in pregnancies complicated with fetal growth restriction
Authors : Seyit Ahmet Erol, Nur Gözde Kulhan, Oğuzhan Günenc
Pages : 1617-1624
Doi:10.38136/jgon.1195083
View : 14 | Download : 7
Publication Date : 2023-03-30
Article Type : Research
Abstract :Aim: To evaluate fetal thymus size using the thymic-thoracic ratio (TTR) in women with a pregnancy complicated with fetal growth restriction (FGR) and to assess the relationship with adverse perinatal outcomes. Materials and Method: A total of 35 pregnant women with FGR and 42 healthy pregnant women with similar demographic characteristics were included in this prospective study. In the FGR group, cases with pathological doppler flow parameters of absent end-diastolic flow (AEDF) in an umbilical artery and cerebroplacental ratio (CPR) 0.05). The fetal TTR was determined to be significantly lower in the FGR group than in the control group (0.37±0.02 [0.33-0.42] and 0.40±0.02 [0.36-0.45], p<0.001, respectively). A statistically significant, negative moderate correlation was determined between fetal TTR and the EFW <3rd percentile, pathological doppler flow (AEDF and CPR<1) (r= -0.703, r= -0.588, r= -0.383, r= -0.418 and p<0.001, p<0.001, p=0.023, p=0.012, respectively). Conclusion: This is the first study to have evaluated the fetal TTR measurement in FGR-complicated pregnancies. A lower fetal TTR supports the relationship between FGR and fetal thymic involution. Moreover, fetal TTR might be a sonographic indicator for predicting adverse perinatal outcomes.Keywords : Fetal büyüme kısıtlılığı, timik-torasik oran, ultrason