- Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
- Vol: 11 Issue: 2
- Synthesis and Enantiomeric Recognition Studies of Novel C2-Symmetrical Chiral Tetra-Amide Compounds
Synthesis and Enantiomeric Recognition Studies of Novel C2-Symmetrical Chiral Tetra-Amide Compounds
Authors : Murat Sünkür, Züleyha Tiğiz, Deniz Cebe, Tarık Aral
Pages : 1293-1301
Doi:10.21597/jist.802116
View : 15 | Download : 2
Publication Date : 2021-06-01
Article Type : Research
Abstract :Two novel C2-symmetrical chiral tetraamide compounds derived from (S)-isoleucine were synthesised and their enantiomeric recognition abilities towards enantiomers of some amino acid esters and 1-arylethylamins were examined by UV-titration method. These receptor compounds exhibited strong complexation (with Ka up to 5787.23 M-1) and very good enantioselectivity (up to KaS/KaR= 13.98).Keywords : Enantiomeric recognitionon, chiral amide, C2-symmetrical amino acid esters, molecular recognition