- Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
- Vol: 10 Issue: 3
- Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound
Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound
Authors : Parham Taslimi
Pages : 1857-1864
Doi:10.21597/jist.732018
View : 16 | Download : 10
Publication Date : 2020-09-01
Article Type : Research
Abstract :In this paper, we investigated the antioxidant potential of Quebecol in vitro using several assays. These; Cu2+-Cu+ reducing, DPPH• scavenging, Fe3+-Fe2+reducing, ABTS•+ scavenging. The IC50 amounts of the Quebecol in the DPPH• and ABTS•+ methods were 14.78 and 5.38 μg m1, respectively. Tyrosinase enzyme is a functional oxidase that is extensively divided in nature. It is the main enzyme in melanin synthesis and also is involved in designating the color of mammalian hair and skin. Recently, there has been a remarkable concern to study the inhibitory activity of the tyrosinase enzyme and some inhibitory molecules isolated from natural sources. For tyrosinase enzyme, Quebecol and kojic Acid (Standard) as natural phenols have IC50 values of 4.64 and 9.28 μM.Keywords : Quebecol, antioxidant activity, tyrosinase, enzyme inhibition