- Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
- Vol: 9 Issue: 1
- One-Pot Synthesis of Substituted Phthalazine-5,10-dione Derivatives in the Presence of Triflate Cata...
One-Pot Synthesis of Substituted Phthalazine-5,10-dione Derivatives in the Presence of Triflate Catalyst
Authors : Kadir Turhan
Pages : 468-478
Doi:10.21597/jist.433331
View : 14 | Download : 6
Publication Date : 2019-03-01
Article Type : Research
Abstract :In this study, substituted 1 H -pyrazolo[1,2- b ]phthalazine-5,10-diones which are considered that may possess biological activity have been obtained via one-pot multi-component cyclocondensation reaction of phthalhydrazide, aromatic aldehydes and malononitrile catalyzed in the presence of Cu(OTf) 2 in very good yields and short times. The structures of all these synthesized compounds (4a-f) have been determined and characterized by infrared, nuclear magnetic resonance, mass spectral data, and elemental analysis.Keywords : triflate, one-pot, Phthalazinedione, multicomponent, green chemistry