- Genel Tıp Dergisi
- Vol: 33 Issue: 3
- Is There Any Correlation Between the Systemic Immune Inflammatory Index and Disease Severity in Knee...
Is There Any Correlation Between the Systemic Immune Inflammatory Index and Disease Severity in Knee Osteoarthritis?
Authors : Savaş Karpuz, Ramazan Yilmaz, Mehmet Özkan, Ismail Hakkı Tunçez, Eser Kalaoğlu, Halim Yilmaz
Pages : 305-308
Doi:10.54005/geneltip.1228775
View : 85 | Download : 97
Publication Date : 2023-06-30
Article Type : Research Article
Abstract :Objective:The purpose of this study is to investigate the utility of systemic immune inflammation index as a predictor of disease severity in patients with knee osteoarthritis. Methods: 200 patients diagnosed with knee osteoarthritis according to ACR knee osteoarthritis diagnostic criteria were included in the study. Kellgren-Lawrence staging of knee osteoarthritis, Western Ontario and McMaster University Osteoarthritis (WOMAC) index score and systemic immune-inflammation index score were calculated among all participants Results: There were 152 (%76) female and 48 (%24) male participants and median score of age was 63 (54,25-70). 14 (7%) grade 1 gonarthrosis, 64 (32%) grade 2, 72 (36%) grade 3 and 50 (25%) grade 4 gonarthrosis patients were detected. There was no significant correlation between the systemic immune-inflammation index and the radiological stage of gonarthrosis (Kellgren Lawrens Score) (p=0.238). No statistically significant correlation was found between the systemic immune-inflammation index and WOMAC scores (p=0.593). Conclusion: The systemic immune-inflammation index was not found to be correlated with disease severity in knee OA.Keywords : Diz osteoartriti, Enflamasyon mediatörleri, Hastalık şiddeti, Sistemik immün inflamatuar indeks, Knee osteoarthritis, inflammation mediators, disease severity, systemic immune-inflammation index