- Çocuk Dergisi
- Cilt: 23 Sayı: 3
- Comparison of Diagnostic Efficacy of Lancet, Multi-Head Applicator, and Specific Immunoglobulin E in...
Comparison of Diagnostic Efficacy of Lancet, Multi-Head Applicator, and Specific Immunoglobulin E in Allergy Testing
Authors : Serdar Al, Cigdem Aydogmus
Pages : 53-61
Doi:10.26650/jchild.2023.1341124
View : 59 | Download : 90
Publication Date : 2023-10-24
Article Type : Research
Abstract :Objective: Allergic rhinitis and allergic asthma are common respiratory diseases in children. Skin prick tests (SPT) and allergen-specific immunoglobulin E (SpIgE) measurements play a crucial role in their diagnosis. In recent years, the use of rapid diagnostic kits has increased. This study aimed to investigate the diagnostic performance of multiheaded applicator and allergen SpIgE compared to the gold standard lanset. Materials and Methods: Skin prick tests were conducted on the same patients using both a multi-headed applicator and lancet with the same allergen solutions. Additionally, allergen SpIgE levels were measured for each patient. The diagnostic performances of multi-headed applicator and allergen SpIgE were statistically compared to those of lancet. Results: A total of 2100 SPTs were performed on 105 patients, from whom allergen SpIgE levels were also obtained. Allergen sensitivities were detected in order of prevalence as house dust mites, pollens, and molds. Sensitization rates were found to be 73.3% for multi-headed applicators, 82.9% for lanset, and 81% for SpIgE. The diagnostic sensitivity of the multiheaded applicator ranged from 0% to 52%, and its correlations with lanset were weak. Conclusion: Rapid-result tests aimed at allergen sensitivity assessment showed limited effectiveness. The use of accurate and reliable diagnostic methods such as lancet-based SPT and SpIgE measurements is crucial. This study holds the distinction of being the first to evaluate different SPT methods using allergen solutions, providing important insights for accurate diagnosis and treatment of allergic diseases.Keywords : deri testleri, duyarlılık ve özgüllük, ekipman ve malzemeler, çocuklar, alerji