- Çocuk Dergisi
- Vol: 23 Issue: 1
- Hepatitis B antibody Response in Patients with Celiac and Inflammatory Bowel Diseases
Hepatitis B antibody Response in Patients with Celiac and Inflammatory Bowel Diseases
Authors : Didem Gülcü Taşkin
Pages : 79-83
Doi:10.26650/jchild.2023.1178024
View : 5 | Download : 3
Publication Date : 2023-03-27
Article Type : Research
Abstract :Objective: In some patient groups, special vaccination protocols need to be followed for vaccine preventable diseases like Hepatitis B (HB). We aimed to evaluate the antibody response against the HB vaccine in Inflammatory Bowel Disease (IBD) and Celiac Disease (CD) patients, emphasizing the efficiency of the routine vaccine protocol for these patient groups. Material and Methods: We included 219 patients (CD and IBD) and 125 in the healthy control group (HCG). The patients who had received only 3 doses of HB vaccine were included. The design of the study is retrospective in manner. Results: The patients age with positive antibody (anti-HBs titers) were lower than in patients with negative anti-HBs titers. In patients having positive anti-HBs titers, both the serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) values were found to be significantly higher. Result: Following periodic control measures and administering an additional dose of the HB vaccine is required because the antibody protection decreases as the illness continues to progress with the increasing age of the patients.Keywords : Çölyak Hastalığı (ÇH), Hepatit B virüs aşısı, Anti HBs antikor titresi, İnflammatuvar bağırsak hastalığı (İBH), çocuk