- Adıyaman Üniversitesi Fen Bilimleri Dergisi
- Vol: 10 Issue: 1
- Toxic Effects of Glyphosate-Based Herbicide on Melanopsis praemorsa
Toxic Effects of Glyphosate-Based Herbicide on Melanopsis praemorsa
Authors : Özlem DEMİRCİ, Feysel ÇAKMAK, Ahmet İsmail ÖZKAN
Pages : 10-21
Doi:10.37094/adyujsci.623260
View : 22 | Download : 3
Publication Date : 2020-06-25
Article Type : Research
Abstract : In the present study, we determined the 24, 48, 72, and 96 h LC50 values for a glyphosate- based commercial herbicide (GBH) for the aquatic snail Melanopsis praemorsa. We examined subacute toxicity responses from M. praemorsa after 30-day exposure to 1/10, 1/5, and 1/2 of the 96 h LC50 value using several biochemical markers. Glutathione reductase (GR) and glutathione S-transferase (GST) activities were significantly inhibited when compared to control after 4 days of GBH exposure. On the twentieth day of exposure, GST and GR activities were inhibited in organisms exposed to both LC50/10 and LC50/5 compared to control. These results showed that chronic GBH exposure inhibited GST, an important detoxifying enzyme. GR, an important oxidative stress marker, was likely inhibited as a result of inhibition of the detoxification mechanism.Keywords : Melanopsis praemorsa, Biomarkers, Glyphosate-based herbicide