- Cumhuriyet Üniversitesi Fen-Edebiyat Fakültesi Fen Bilimleri Dergisi
- Vol: 36 Issue: 3
- Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test
Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test
Authors : Tofigh Taherkhani, Rasool Asghari Zakaria, Mahboubeh Taherkhani
Pages : 1682-1687
View : 9 | Download : 3
Publication Date : 2015-05-13
Article Type : Review
Abstract :Abstract. The aim of this study was to determine the mutagenic and anti-mutagenic properties of the essential oil of Jurinea leptoloba DC in vitro . The mutagenic and anti-mutagenic activities of the oil was evaluated using the Salmonella typhimurium tester strains TA98 and TA100, together with nitrofluorene for TA98 and sodium azide for TA100 without (-S9) metabolic activation, and 2-aminoantracene for TA98 and TA100 with metabolic (+S9) activation. The results obtained with S. typhimurium suggest that the oil of J. leptoloba can not be exploited as an anti-mutagenic agent with low adverse side effects.Keywords : Jurinea leptoloba, Essential oil, Mutagenic, Anti-mutagenic