- Bitlis Eren Üniversitesi Fen Bilimleri Dergisi
- Vol: 12 Issue: 1
- The Combined Use of SCD Probiotics and Tauroursodeoksikolik Asit (TUDCA) is More Effective in Contro...
The Combined Use of SCD Probiotics and Tauroursodeoksikolik Asit (TUDCA) is More Effective in Controlling Anxiety-Like Behavior in Aged Rats
Authors : Taha Ceylani, Hikmet Taner Teker
Pages : 242-246
Doi:10.17798/bitlisfen.1231238
View : 8 | Download : 3
Publication Date : 2023-03-22
Article Type : Research
Abstract :In this study, the effects of TUDCA administration with a SCD probiotics for one week on locomotors activity and anxious behavior were investigated. Male Saprague-Dawley rats aged 24 months were used as the model organism. At the end of the application, open-field and elevated plus maze behavioral tests were performed on the rats. Although SCD probiotics were more effective on anxious behavior, the group in which they were administered together had a significantly greater effect on locomotor activity and anxious behavior. This study provides important evidence that combining SCD probiotics and TUDCA administration may be more beneficial to behavior.Keywords : TUDCA, SCD probiotics, OF, EPM, Anxiety.