- Turkish Computational and Theoretical Chemistry
- Vol: 7 Issue: 3
- Mimic toxicity of Beta-blocker drugs by structural base descriptors
Mimic toxicity of Beta-blocker drugs by structural base descriptors
Authors : Akshay Tiwari
Pages : 24-29
Doi:10.33435/tcandtc.1196259
View : 40 | Download : 48
Publication Date : 2023-09-03
Article Type : Research Article
Abstract :QSAR study has been carried out on the set of 35 Beta-blocker drugs for the modelling of toxicity (Ld50), using topological indices. The stepwise multilinear regression analysis method is used for modelling and the obtained models are critically discussed and examined by various types of cross validation parametersKeywords : Beta-Blockers, LD50, topological index, regression analysis, Beta-Blockers, LD50, topological index, regression analysis