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- Is there a relationship between Diffusion Weighted Imaging and Histopathological Type in Brain Metas...
Is there a relationship between Diffusion Weighted Imaging and Histopathological Type in Brain Metastases Due to Breast Cancer?
Authors : Şeyhmus Kavak, Nazan Çiledağ
Pages : 133-139
Doi:10.33631/sabd.1346821
View : 13 | Download : 44
Publication Date : 2024-01-16
Article Type : Research
Abstract :Aim: The aim of this study is to evaluate the relationship between diffusion-weighted imaging (DWI) properties and apparent diffusion coefficient (ADC) values of metastases with the histological type of breast cancer in patients with breast cancer-related brain metastasis. Material and Methods: Between May 2008 - April 2011, 57 female patients who had been previously diagnosed with breast cancer in the radiology clinic were included in the study. Cases with invasive ductal carcinoma were considered group 1 (46 patients, 89 lesions) and cases with invasive lobular, comedo carcinoma and papillary cribriform carcinoma were considered group 2 ( 11 patients, 25 lesions). ADC values in both groups were compared by statistical analysis methods. Results: In group 1; 37 lesions (41.57%) and in group 2; 13 lesions (52%) included cystic component. In the group of invasive ductal carcinoma 48 lesions (53.92%) and 18 lesions (72%) of second group included peritumoral edema. The mean ADC value of the solid component of metastases (group1: 1.105x10-3mm2/ s, group2: 1.099x10-3mm2/ s) was higher than the average ADC value of normal brain parenchyma (group1: 0.790x10-3mm2/s, group2: 0.801x10-3mm2/s), and was statistically significant (p<0.001). In the comparison between the groups, no statistically significant difference was found between the mean ADC values of the solid components of metastases (p= 0.931). Conclusion: In our study, mean ADC values in brain metastases due to breast cancer were significantly higher than normal brain parenchyma. However, no statistically significant difference was found in the comparison of ADC values of the groups formed according to histopathological subtypes.Keywords : Meme Kanseri, Difüzyon Ağırlıklı Görüntüleme, Görünür Difüzyon Katsayısı