- Pediatric Practice and Research
- Vol: 7 Issue: 2
- Screening for G6PD Enzyme Deficiency Among Children aged Five Years and Below in Diyala Province / I...
Screening for G6PD Enzyme Deficiency Among Children aged Five Years and Below in Diyala Province / Iraq.
Authors : Jalil Ibrahim Al-ezzi
Pages : 9-14
View : 10 | Download : 3
Publication Date : 2019-08-31
Article Type : Research
Abstract :Background: G6PD deficiency is the most common gene mutation in the world and the numerous mutations have been classified by the WHO. Objective: is to estimate the prevalence of G6PD enzyme deficiency among ≤5 years old children attending Al Batool Obstetrics and Pediatric Teaching Hospital in Baqubah city, Diyala, Iraq, and to see whether screening for G6PD enzyme deficiency is worthy. Study setting, design and sample size: A hospital based observational cross-sectional study consisting of 1500 children (820 boys and 680 girls), in children aged 5 years and below who attended Al Batool Obstetrics and Pediatric Teaching Hospital in Baqubah city, Diyala, Iraq during period from December 1 st 2018 to June30 th 2019. Blood samples were collected from each child and analyzed for Hemoglobin (Hb) level, and G6PD enzyme activity assay. Results: Out of 1500 children tested for enzyme activity only 20 children (1.33%) had low enzyme activity. Conclusion: The prevalence of G6PD enzyme deficiency is low, so screening for the enzyme deficiency is not warranted at least in Diyala province.Keywords : Screening, G6PD, children