- Acta Medica Alanya
- Cilt: 7 Sayı: 2
- Association of Hypophosphatemia with Morbidity and Mortality in Patients with COVID-19
Association of Hypophosphatemia with Morbidity and Mortality in Patients with COVID-19
Authors : Faruk Karandere, Deniz Yilmaz, Felemez Arslan, Ezgi Şahin, Sema Koyuncu
Pages : 137-144
Doi:10.30565/medalanya.1296968
View : 62 | Download : 118
Publication Date : 2023-10-29
Article Type : Research
Abstract :Aim: In critical cases, electrolyte disturbances such as hypophosphatemia have been shown to be associated with mortality and in our study, we aimed to examine the relationship between hypophosphatemia, a symptom disorder with COVID-19, and death. Material and Methods: This study is a retrospective, cross-sectional investigation that encompasses patients diagnosed with COVID-19 and subsequently admitted for treatment at our hospital. Based on their serum phosphate levels, the patients were bifurcated into two distinct categories: those with serum phosphate levels below 2.5 mg/dl, classified as hypophosphatemic, and those with levels above this benchmark, categorized as non-hypophosphatemic. The comparisons drawn between these two cohorts were facilitated using a range of statistical methodologies, and the resulting findings were subsequently analyzed and interpreted within this framework. Results: Compared to the hypophosphatemia group, the diagnoses of DM (p<0.001) and CKD (p=0.015) were statistically significantly higher in the group without hypophosphatemia. A statistically significant difference was found between phosphorus groups and mortality and length of stay (p<0.001). In addition, age and length of hospitalization were found to be statistically significantly higher in those who died compared to those who were alive (p<0.001; p=0.002). Conclusions: Hypophosphatemia has been shown to be associated with mortality in patients with COVID-19, as in many studies and in our study, and it may be a biomarker in predicting severe disease.Keywords : COVİD-19, Fosfor, Diyabetis Mellitus, Mortalite