- Communications Faculty of Sciences University Ankara Series C Biology
- Vol: 29 Issue: 1
- ANTIMUTAGENIC AND ANTIOXIDANT ACTIVITIES OF TEUCRIUM MULTICAULE AND ITS CYTOTOXIC EFFECT ON MURINE L...
ANTIMUTAGENIC AND ANTIOXIDANT ACTIVITIES OF TEUCRIUM MULTICAULE AND ITS CYTOTOXIC EFFECT ON MURINE LR7 CELL
Authors : Mustafa Pehlivan, Önder Yumrutaş, Ibrahim Bozgeyik
Pages : 95-104
View : 17 | Download : 2
Publication Date : 2020-06-30
Article Type : Research
Abstract :In present study, DNA protection, antioxidant and cytotoxic effects of Teucrium multicaule Montbret Et Aucher Ex Bentham methanol extract (TME) was investigated. Cytotoxic effects and antioxidant activities of TME was determined by MTT and DPPH scavenging and DNA protection methods. As a result, high dose of TME exhibited a cytotoxic effect on murine L cells. Although, TME also showed a strong antimutagenic activity in DNA protection test system, it exhibited modest activity in DPPH test system. Consequently, it may be used as natural agent for antioxidant and antimutagenic properties.Keywords : Cytotoxicity, DNA protection, Antioxidant, Antimutagenic, Teucrium multicaule