- Avrasya Sağlık Bilimleri Dergisi
- Vol: 1 Issue: 1
- Investigation of In-Vitro Antibacterial Activity of Curcuma longa Commercial Extract
Investigation of In-Vitro Antibacterial Activity of Curcuma longa Commercial Extract
Authors : Şinasi Aşkar, Şeyma Nur Deveboynu
Pages : 1-6
View : 47 | Download : 11
Publication Date : 2018-06-29
Article Type : Research
Abstract :New plant-derived antibacterial agent researches have increased in recent years, because of increased resistance to antimicrobial agents that used against to pathogen microorganisms, and unwanted side effects of food additives. The aim of this research was to investigate the, in-vitro antibacterial activities and minimal inhibitory concentration of Curcuma longa which obtained from India, commercial plant extracts against some nosocomial pathogens (Extended Spectrum Beta Lactamase Escherichia coli , Klebsiella pneumoniae , Pseudomonas aeruginosa, Enterococcus faecalis , Methicillin Resistant Staphylococcus aureus) , by disk diffusion and broth microdilution methods. The diameter of the inhibition zone in the disc-diffusion method shows that Curcuma longa extract (6.12 mg/disc) has antibacterial activity only on MRSA (Inhibition zone diameter 8 mm). However, with broth micro dilution method, Curcuma longa extract had minimal inhibitor concentration (4.87-78 mg/ml) on all bacteria in different levels. Curcuma longa extract showed the minimum MIC value on S.aureus , maximum MIC value on E.coli, K.pneumoniae and E. faecalis. The results were consistent in both methods at equal concentrations applied from the Curcuma longa extract. In conclusion, particularly Curcuma longa leaf extract is thought to be effective against to MRSA, E. coli , K. pneumoniae , P. aeruginosa , E. faecalis in many areas like medical and food industries. However, there are need new in vivo studies in future.Keywords : Broth microdilution, Disk diffusion, Inhibition, Nosocomial