- Animal Health Production and Hygiene
- Cilt: 12 Sayı: 2
- Effect of Vitamin C on Oxidant and Antioxidant Parameters in Cattle Immunized by Blackleg Vaccine
Effect of Vitamin C on Oxidant and Antioxidant Parameters in Cattle Immunized by Blackleg Vaccine
Authors : Ertan Doğan, Oğuz Merhan, Hale Ergin Eğritağ, Kadir Bozukluhan, Dinçer Erdağ
Pages : 7-12
Doi:10.53913/aduveterinary.1307606
View : 67 | Download : 86
Publication Date : 2023-12-26
Article Type : Research
Abstract :The goal of this study is to determine the effect of vitamin c on certain oxidant and antioxidant parameters in cattle immunized against blackleg. In the study, a total of 40 cattle aged 12 to 18 months, of different breeds and genders, were used in the Ardahan region. The cattle were divided into four equal groups. The Control group received 2 ml of saline, the Vitamin group received 5 mg/kg dose of vitamin c, the Vaccine-Vitamin group received 2 ml of blackleg vaccine and 5mg/kg vitamin c, and the Vaccine group received 2 ml of blackleg vaccine. Blood samples were taken from all animals before vaccination (day 0) and on the 2nd, 14th, and 28th days of administration. On the 2nd, 14th, and 28th days, malondialdehyde (MDA) and nitric oxide (NO) levels were substantially increased (P<0.05) in the Vaccine group compared to the Control and Vitamin groups, while superoxide dismutase (SOD) and catalase (CAT) levels were considerably decreased (P<0.05). It was noted that the amount of MDA and NO measured in the 2nd, 14th, and 28th days in the Vaccine-Vitamin group reduced compared to the Vaccine group, while the amount of SOD and CAT enhanced. The study concluded that the blackleg vaccine administered to cattle causes oxidative stress and lipid peroxidation, and that vitamin c acts as an antioxidant. Vitamin c administration with blackleg vaccine in cattle is believed to be beneficial for lowering oxidative stress.Keywords : C vitamini, Lipid Peroksidasyonu, Oksidatif stres, Sığır, Yanıkara aşısı