- Turkish Journal of Analytical Chemistry
- Vol: 2 Issue: 1
- Preparation of cobalt oxide/gold nanoparticle modified glassy carbon electrode for electrochemical d...
Preparation of cobalt oxide/gold nanoparticle modified glassy carbon electrode for electrochemical detection of dopamine
Authors : Ceren Kuşcu, Volkan Özdokur, Süleyman Koçak, Fatma Nil Ertas
Pages : 15-21
View : 13 | Download : 5
Publication Date : 2020-06-23
Article Type : Research
Abstract :This study deals with electrochemical preparation of cobalt oxide modified glassy carbon electrodes decorated with gold nanoparticles as an effective platform for dopamine (DA) detection. The experimental parameters affecting the oxidation signal of DA by square wave voltammetry have been evaluated. Under optimal conditions, developed sensor exhibited a linear response towards to DA in the concentration range of 6.0 10−8 to 7.5 10−6 M. The detection and quantification limits were calculated as 2.0 10−8 and 6.0 10−8M, respectively. The repeatability and reproducibility of the electrode were calculated as 13.2 and 16.1 % for 6.5 10-7 M (N = 3), respectively. Finally, the sensor was successfully applied for the DA analysis in artificial cerebrospinal fluid, and the mean recovery was found as 105.8 ±6.5 % by standard addition method.Keywords : Dopamine, square wave voltammetry, cobalt oxide