- Turkish Journal of Internal Medicine
- Vol: 1 Issue: 1
- Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney t...
Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients
Authors : Mehmet Usta, Alparslan Ersoy, Yavuz Ayar
Pages : 21-25
Doi:10.46310/tjim.632066
View : 12 | Download : 4
Publication Date : 2019-10-29
Article Type : Research
Abstract :Abstract Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation. Methods : Thirteen of all recipients were taking a cyclosporine-based regimen and serum creatinine levels were above 1.5 mg/dL. In 13 patients, MPA treatment was started instead of AZA. Renal functions were evaluated for 12 months after MPA treatment. Results : Serum creatinine levels increased from 2.11±0.48 mg/dL to 2.16±0.72 mg/dL at 12th months. This increase was not statistically significant. Serum creatinine levels decreased in 5 of 13 patients. Conclusion : In selected patients, conversion from AZA to MPA may slow down the rate of deterioration in graft functions.Keywords : azathioprine, mycophenolate mofetil, kidney transplantation recipient