- Turkish Journal of Clinics and Laboratory
- Vol: 14 Issue: 2
- Carotid Body Enlargement in Patients with Hypertension and Comorbid Diseases: a CT Angiographic Stud...
Carotid Body Enlargement in Patients with Hypertension and Comorbid Diseases: a CT Angiographic Study
Authors : Gözde Özer, Lale Damgaci
Pages : 299-305
Doi:10.18663/tjcl.1264052
View : 12 | Download : 18
Publication Date : 2023-06-30
Article Type : Research Article
Abstract :Aim: To determine the carotid body (CB) size and its relationship with hypertension, other sympathetically mediated disorders and smoking. Materials and Methods: Neck CT angiographies of 180 patients performed in our clinic in the previous year were included in the study. The patients\' histories were assessed for hypertension (HT), congestive heart failure (CHF), diabetes mellitus (DM), chronic obstructive pulmonary disease and smoking. The study groups were smokers without any chronic condition (S group, n=21), patients with HT alone (HT group, n=26), patients that had at least two chronic disorders (CD+S group, n=78) and the controls (n=33). The widest axial diameter of the CB was measured on axial sections. Results: CB diameter could be measured in 158 patients. The CB diameter was significantly greater in HT (2.77±3.28 mm, p=0.02) and CD+S (2.76±3.38 mm, p<0.01) groups compared to the controls (2.22±3.41 mm). There was no significant difference between the S group (2.47±3.44 mm) and the control group (p=0.123). Repeated measurements showed a high intra-observer correlation for both sides. Conclusion: HT causes a significant increase in CB size. CB size also increases significantly in individuals with the combination of sympathetically mediated disorders, including HT, CHF, and DM. CTA may provide a better understanding of the relationship between CB and sympathetically mediated diseases and guide further studies as well as therapies targeting CB.Keywords : bilgisayarlı tomografi, karotid cisim, hipertansiyon